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Trandate (generic name: labetalol; brand names include: Normodyne) belongs to a group of medicines known as alpha/beta adrenergic antagonists.


What should I tell my health care provider before I take Labetalol?

They need to know if you have any of these conditions:

•   diabetes
•   history of heart attack, heart disease or heart failure
•   kidney disease
•   liver disease
•   lung or breathing disease, like asthma or emphysema
•   pheochromocytoma
•   thyroid disease
•   an unusual or allergic reaction to labetalol, other beta-blockers, medicines, foods, dyes, or preservatives
•   pregnant or trying to get pregnant
•   breast-feeding


How should I use Labetalol?

Take this medicine by mouth with a glass of water. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine suddenly. This could lead to serious heart-related effects.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.
What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with Labetalol?

Do not take this medicine with any of the following medications:

•   sotalol

This medicine may also interact with the following medications:

•   cimetidine
•   diltiazem
•   general anesthetics
•   medicines for asthma or lung disease like albuterol
•   medicines for high blood pressure
•   medicines for depression
•   nitroglycerin
•   verapamil

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using Labetalol?

Visit your doctor or health care professional for regular check ups. Check your blood pressure and pulse rate regularly. Ask your health care professional what your blood pressure and pulse rate should be, and when you should contact him or her.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

This medicine can affect blood sugar levels. If you have diabetes, check with your doctor or health care professional before you change your diet or the dose of your diabetic medicine.

Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care professional for advice. Some ingredients may increase your blood pressure.
What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

•   allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
•   breathing problems
•   cold hands or feet
•   dark urine
•   depression
•   general ill feeling or flu-like symptoms
•   irregular heartbeat
•   light-colored stools
•   loss of appetite, nausea
•   pain or trouble passing urine
•   right upper belly pain
•   slow heart rate (fewer than recommended by your doctor or health care professional)
•   swollen legs or ankles
•   tingling of the scalp or skin
•   unusually weak or tired
•   vomiting
•   yellowing of the eyes or skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

•   decreased sexual function or desire
•   dry itching skin
•   headache
•   tiredness

This list may not describe all possible side effects.

Where should I keep Labetalol?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.

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